Using Retin A (Tretinoin)

It is very important that you use Retin A (Tretinoin) only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irritation of the skin.

Do not apply Retin A (Tretinoin) to windburned or sunburned skin or on open wounds.

Do not use Retin A (Tretinoin) in or around the eyes or lips, or inside of the nose. Spread the medicine away from these areas when applying. If the medicine accidentally gets on these areas, wash with water at once.

Retin A (Tretinoin) usually comes with patient directions. Read them carefully before using the medicine.

Before applying Retin A (Tretinoin), wash the skin with a mild soap or cleanser and warm water by using the tips of your fingers. Then gently pat dry. Do not scrub your face with a sponge or washcloth. Wait 20 to 30 minutes before applying Retin A (Tretinoin) to make sure the skin is completely dry. Applying Retin A (Tretinoin) to wet skin can irritate the skin.

To use the cream or gel form of Retin A (Tretinoin):

Apply just enough medicine to very lightly cover the affected areas, and rub in gently but well. A pea-sized amount is enough to cover the whole face.
To use the solution form of Retin A (Tretinoin):

Using your fingertips, a gauze pad, or a cotton swab, apply enough Retin A (Tretinoin) solution to cover the affected areas. If you use a gauze pad or a cotton swab for applying the medicine, avoid getting it too wet. This will help prevent the medicine from running into areas not intended for treatment.
After applying the medicine, wash your hands to remove any medicine that might remain on them.

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Dose of Retin A (Tretinoin) ointment:

The dose of topical Retin A (Tretinoin) will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average dose of topical Retin A (Tretinoin). If your dose is different, do not change it unless your doctor tells you to do so.

For topical dosage forms (cream, gel, or solution):
For acne:
Adults and teenagers—Apply to the affected area(s) of the skin once a day, at bedtime.

For cream dosage form (brand name Renova only):
For fine wrinkles, dark spots, or rough skin caused by the sun:
Adults up to 50 years of age—Apply to the affected area(s) of the skin once a day, at bedtime.
Adults 50 years of age and older—Use and dose must be determined by your doctor.

Missed Dose of Retin A (Tretinoin)

If you miss a dose of Retin A (Tretinoin) , apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage of Retin A (Tretinoin)

  • Keep out of the reach of children.
  • Store away from heat and direct light.
  • Store away from heat and direct light. The gel product is flammable and should be kept away from fire or excessive heat.
  • Keep the medicine from freezing.
  • Do not keep outdated Retin A (Tretinoin) or Retin A (Tretinoin) tablets that are no longer needed.
  • Be sure that any discarded medicine is out of the reach of children.


Precautions While Using Retin A (Tretinoin)

During the first 3 weeks you are using Retin A (Tretinoin), your skin may become irritated. Also, your acne may seem to get worse before it gets better. It may take longer than 12 weeks before you notice full improvement of your acne, even if you use the medicine every day. Check with your health care professional at any time skin irritation becomes severe or if your acne does not improve within 8 to 12 weeks.

You should avoid washing the skin treated with Retin A (Tretinoin) for at least 1 hour after applying it.

Avoid using any topical medicine on the same area within 1 hour before or after using Retin A (Tretinoin). Otherwise, Retin A (Tretinoin) may not work properly or skin irritation might occur.

Unless your doctor tells you otherwise, it is especially important to avoid using the following skin products on the same area as Retin A (Tretinoin):

Any other topical acne product or skin product containing a peeling agent (such as benzoyl peroxide, resorcinol, salicylic acid, or sulfur)
Hair products that are irritating, such as permanents or hair removal products
Skin products that cause sensitivity to the sun, such as those containing spices or limes
Skin products containing a large amount of alcohol, such as astringents, shaving creams, or after-shave lotions
Skin products that are too drying or abrasive, such as some cosmetics, soaps, or skin cleansers
Using these products along with Retin A (Tretinoin) may cause mild to severe irritation of the skin. Although skin irritation can occur, some doctors sometimes allow benzoyl peroxide to be used with Retin A (Tretinoin) to treat acne. Usually Retin A (Tretinoin) is applied at night so that it does not cause a problem with any other topical products that you might use during the day. Check with your doctor before using topical medicines with Retin A (Tretinoin).

During the first 6 months of use, avoid overexposing the treated areas to sunlight, wind, or cold weather. The skin will be more prone to sunburn, dryness, or irritation, especially during the first 2 or 3 weeks. However, you should not stop using Retin A (Tretinoin) unless the skin irritation becomes too severe. Do not use a sunlamp .

To help Retin A (Tretinoin) work properly, regularly use sunscreen or sunblocking lotions with a sun protection factor (SPF) of at least 15. Also, wear protective clothing and hats, and apply creams, lotions, or moisturizers often.

Check with your doctor at any time your skin becomes too dry and irritated. Your health care professional can help you choose the right skin products for you to reduce skin dryness and irritation and may include the following:

For patients using Retin A (Tretinoin) for the treatment of acne:
Regular use of water-based creams or lotions helps to reduce skin irritation or dryness that may be caused by the use of Retin A (Tretinoin).
For patients using Retin A (Tretinoin) for the treatment of fine wrinkling, dark spots, and rough skin caused by the sun:
Retin A (Tretinoin) should be used as part of an ongoing program to avoid further damage to your skin from the sun. This program includes staying out of the sun when possible or wearing proper clothing or hats to protect your skin from sunlight.
Regular use of oil-based creams or lotions helps to reduce skin irritation or dryness caused by the use of Retin A (Tretinoin).

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Side Effects of Retin A (Tretinoin)

In some animal studies, Retin A (Tretinoin) has been shown to cause skin tumors to develop faster when the treated area is exposed to ultraviolet light (sunlight or artificial sunlight from a sunlamp). Other studies have not shown the same result and more studies need to be done. It is not known if Retin A (Tretinoin) causes skin tumors to develop faster in humans.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common
Burning feeling or stinging skin (severe); lightening of skin of treated area, unexpected; peeling of skin (severe); redness of skin (severe) ; unusual dryness of skin (severe)


Rare
Darkening of treated skin


Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common
Burning feeling, stinging, or tingling of skin (mild)—lasting for a short time after first applying the medicine; chapping or slight peeling of skin (mild); redness of skin (mild); unusual dryness of skin (mild); unusually warm skin (mild)

The side effects will go away after you stop using Retin A (Tretinoin). On the rare chance that your skin color changes, this effect may last for several months before your skin color returns to normal.

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

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Retin A (Tretinoin)

Retin A (Tretinoin) (TRET-i-noyn) is used to treat acne. It is also known as Avita, Renova, Retisol-A, Stieva-A and works partly by keeping skin pores clear.

One of the Retin A (Tretinoin) creams is used to treat fine wrinkles, dark spots, or rough skin on the face caused by damaging rays of the sun. It works by lightening the skin, replacing older skin with newer skin, and by slowing down the way the body removes skin cells that may have been harmed by the sun. Retin A (Tretinoin) works best when used within a skin care program that includes protecting the treated skin from the sun. However, it does not completely or permanently erase these skin problems or greatly improve more obvious changes in the skin, such as deep wrinkles caused by sun or the natural aging process.

Retin A (Tretinoin) may also be used to treat other skin diseases as determined by your doctor.

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